Thermo Fisher Scientific MAP2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MAP2 protein for WB and IHC applications. Recognizes C-terminal epitope (aa 1766–1796). High specificity and purity via Protein A and antigen affinity chromatography. Suitable for neurogenesis and neuron struc...
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- PA511880
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 1766–1796 from the C-terminal region of human MAP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2137878 |
Target Information
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, an essential step in neurogenesis.
The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development.
MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer’s Disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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