Thermo Fisher Scientific IRAK3 Monoclonal Antibody (1F6)
IRAK3 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, Affinity chromatography로 정제된 액상 형태입니다. PBS buffer 보관, 연구용 전용 시약입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F6 |
| Immunogen | IRAK3 (AAH57800, 497–596 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
RIDRMTQKTP FECSQSEVMF LSLDKKPESK RNEEACNMPS SSCEESWFPK YIVPSQDLRP YKVNIDPSSE APGHSCRSRP VESSCSSKFS WDEYEQYKKE
Target Information
IRAK3 (Interleukin-1 receptor-associated kinase 3) is a serine/threonine kinase and member of the IRAK protein family, essential in Toll/IL-R immune signaling pathways. It is primarily expressed in monocytes and macrophages and acts as a negative regulator of Toll-like receptor signaling. IRAK3 plays a key role in innate immunity and is implicated in immunocompromised states during sepsis. Mutations in IRAK3 are associated with susceptibility to asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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