Thermo Fisher Scientific FGL2 Polyclonal Antibody
Human FGL2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 연구용 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA555376
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FGL2. Recombinant protein control fragment (Product #RP-92705) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641617 |
Product Specific Information
- Immunogen sequence:
SQEQIQSRPV QHLIYKDCSD YYAIGKRSSE TYRVTPDPKN SSFEVYCDME TMGGGWTVLQ ARLDGSTNFT RTWQDYKAGF GNLRR - Highest antigen sequence identity to orthologs:
Mouse – 84%, Rat – 85%
Target Information
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases where thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome, and xenograft rejection.
Constitutively expressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on T cell proliferation and dendritic cell maturation.
Fgl2 is a serine protease that directly cleaves prothrombin to thrombin and functions in the pathogenesis of viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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