Thermo Fisher Scientific APRT Polyclonal Antibody
Human APRT 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체. 장기 보관 시 -20°C에서 보관 권장. 연구용 전용 시약.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human APRT. Recombinant protein control fragment (Product #RP-92499). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638096 |
Product Specific Information
Immunogen sequence:
MADSELQLVE QRIRSFPDFP TPGVVFRDIS PVLKDPASFR AAIGLLARHL KATHGGRIDY IAGD
Highest antigen sequence identity to orthologs:
- Mouse: 73%
- Rat: 78%
Target Information
Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family.
This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP).
It also produces adenine as a by-product of the polyamine biosynthesis pathway.
A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.
Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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