Thermo Fisher Scientific Menin Polyclonal Antibody
Thermo Fisher Scientific의 Menin Polyclonal Antibody는 인간 및 생쥐 시료에서 Menin 단백질 검출에 적합합니다. Western blot 및 면역세포화학(ICC/IF)에 사용 가능하며, 항원 친화 크로마토그래피로 정제된 고순도 항체입니다. 동결건조 형태로 제공되며 재구성 후 500 µg/mL 농도로 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human Menin recombinant protein (Position: P301–L615) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746778 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Potassium channels are ubiquitously expressed proteins that perform multiple functions in both excitable and non-excitable cells. One class, the large conductance calcium-activated potassium channel (Maxi K+), is activated by both intracellular calcium increases and membrane depolarization. This dual activation is enabled by its structure: a Maxi K+ alpha homotetramer containing both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, a beta-subunit associates in a 1:1 ratio, reducing the calcium concentration required to open the channel by 5–10 fold.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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