Thermo Fisher Scientific Adenylosuccinate Lyase/ADSL Polyclonal Antibody
Rabbit polyclonal antibody targeting human Adenylosuccinate Lyase (ADSL). Validated for WB and IP applications. Supplied as liquid, unconjugated form at 1 mg/mL concentration. Recommended storage at 4°C with 1-year shelf life.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200–250 of human Adenylosuccinate lyase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
ADSL (Adenylosuccinate Lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid enzyme involved in purine biosynthesis and AMP formation from inosine monophosphate.
It catalyzes two key reactions in AMP biosynthesis:
- Removal of fumarate from succinylaminoimidazole carboxamide ribotide (SAICA ribotide) to yield aminoimidazole carboxamide ribotide (AICA).
- Removal of fumarate from adenylosuccinate to yield AMP.
Defects in the ADSL gene cause adenylosuccinase deficiency, an autosomal recessive disorder associated with epilepsy, growth retardation, and muscular wasting.
Multiple isoforms exist due to alternative splicing events.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(원본 항원 관련 이미지 및 파일명: A304-778A-M_ADSL_P30566-1_Rabbit.svg, A304-778A-M_ADSL_P30566-1_Rabbit_PDP.jpeg)
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