Thermo Fisher Scientific GSK3B interacting protein Polyclonal Antibody
GSK3B 결합 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 고순도 항체입니다. 연구용으로 Wnt 신호전달 관련 단백질 분석에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Ninein, amino acids 133–230 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein that acts as a negative regulator of GSK3-beta in the Wnt signaling pathway. It may also play a role in the retinoic acid signaling pathway by regulating interactions between GSK3-beta, beta-catenin, and cyclin D1, and by controlling the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, similar to that of Axin, and an evolutionarily conserved RII-binding domain that facilitates binding with protein kinase-A and GSK3-beta, functioning as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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