Thermo Fisher Scientific ARAP3 Polyclonal Antibody
Thermo Fisher Scientific의 ARAP3 Polyclonal Antibody는 Human ARAP3 단백질을 인식하는 Rabbit IgG 항체입니다. Western blot과 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 단백질 발현 및 기능 분석에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ARAP3. Recombinant protein control fragment (Product # RP-90738) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638109 |
Product Specific Information
Immunogen sequence:
MPNSIYFGLD SRGRAQAAQD KAPDSSQISA PTPALRPTTG TVHIMDPGCL YYGVQPVGTP GAPDRRESRG VCQGRAEHRL SRQDLEARED AGYASLELPG DSTLLSPTLE TEETSDDLIS PYASFSF
Highest antigen sequence identity:
- Mouse: 80%
- Rat: 80%
Target Information
Ubiquitin is a conserved 76 amino acid polypeptide that can affect proteasomal degradation of the protein it is bound to or mediate interactions with other proteins related to post-translational modifications. The degradation of cellular regulatory proteins by the ubiquitin pathway is crucial as it controls cellular growth and proliferation. Ubiquitin-dependent proteolysis occurs after covalent attachment of the peptide to a lysine residue of a protein, involving three enzymatic reactions: E1 (activating enzyme), E2 (conjugating enzyme), and E3 (ligase). The E3 enzyme transfers the activated ubiquitin from E2 to a lysine residue on a protein or directly to the substrate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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