Thermo Fisher Scientific ARAP3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ARAP3. Recombinant protein control fragment (Product #RP-90738). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ARAP3,uniProtId:Q8WWN8-1,ncbiNodeId:9606,antigenRange:155-281,antigenLength:1544,antigenImageFileName:PA5-60158_ARAP3_Q8WWN8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-60158_ARAP3_Q8WWN8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638109

Product Specific Information

Immunogen sequence: MPNSIYFGLD SRGRAQAAQD KAPDSSQISA PTPALRPTTG TVHIMDPGCL YYGVQPVGTP GAPDRRESRG VCQGRAEHRL SRQDLEARED AGYASLELPG DSTLLSPTLE TEETSDDLIS PYASFSF

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.

Target Information

Ubiquitin is a conserved 76 amino acid polypeptide and can affect proteasomal degradation of the protein it is bound to, or mediate interactions with other proteins related to post-translational modifications. The degradation of cellular regulatory proteins by the Uubiquitin pathway is important as it controls the cellular growth and proliferation. Ubiquitin-dependent proteolysis occurs after a covalent attachment of the peptide to a lysine residue of a protein, which involves three enzymatic reactions: E1, E2 and E3. The first reaction involves ubiquitin-activating enzyme. The third reaction uses enzyme ubiquitin ligase (E3) to transfer the activated ubiquitin from E2 to a lysine residue on a protein, or directly transfers the ubiquitin from E2 to the substrate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.