Thermo Fisher Scientific RASSF1 Monoclonal Antibody (OTI8E2), TrueMAB
RASSF1 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot과 Immunocytochemistry에 적합합니다. 고순도의 Affinity chromatography 정제 제품이며, PBS/BSA/glycerol 버퍼에 보관됩니다. 암 연구 및 세포주 분석용 연구 전용 시약입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E2 |
| Immunogen | Full length human recombinant protein of human RASSF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The RASSF1 gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of various cancers, suggesting a tumor suppressor function. Inactivation of this gene is correlated with hypermethylation of its CpG-island promoter region. The encoded protein interacts with DNA repair protein XPA and inhibits the accumulation of cyclin D1, inducing cell cycle arrest. Seven alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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