Thermo Fisher Scientific N-WASP Monoclonal Antibody (OTI6A4)
N-WASP 단백질을 타깃으로 하는 Mouse Monoclonal Antibody(OTI6A4)로, Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, 액상 형태로 제공. Affinity Chromatography로 정제되어 높은 특이성과 재현성을 보장. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A4 |
| Immunogen | Full length human recombinant protein of WASL produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724782 |
Target Information
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structures and are involved in the transduction of signals from receptors on the cell surface to the actin cytoskeleton. These proteins are regulated by multiple stimuli and interact with various proteins. N-WASP associates with the small GTPase Cdc42 and the Arp2/3 cytoskeletal organizing complex, regulating actin filament formation. The WASL gene product, a homolog of WAS protein, is ubiquitously expressed with the highest levels in neural tissues and can induce formation of long actin microspikes through direct Cdc42 binding.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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