Thermo Fisher Scientific Human Oncostatin M (209 aa), Animal-Free Recombinant Protein, PeproTech
Animal-free recombinant human Oncostatin M (209 aa) for in vitro functional assays. High purity (≥98%) and low endotoxin (<0.1 EU/µg). Stimulates proliferation of TF-1 cells with ED50 ≤2.0 ng/ml. Lyophilized form for stable storage at -20°C.
- 카탈로그번호
- AF-300-10T-xxx (4개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
4개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Oncostatin M (209 aa), Animal-Free Recombinant Protein, PeproTech
Applications
Functional Assay (Functional)
- Assay-dependent
In Vitro Assay (IV)
- Refer to publication data
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRR |
| Molecular Weight | 23.6 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | Stimulates proliferation of human TF-1 cells (ED50 ≤ 2.0 ng/ml; ≥ 5 x 10^5 units/mg) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human Oncostatin M is a 23.6 kDa protein containing 209 amino acid residues.
This product is shipped at ambient temperature. For storage, handling, and reconstitution details, please refer to the lot-specific Certificate of Analysis.
Target Information
Oncostatin M (OSM) is a growth and differentiation factor involved in neurogenesis, osteogenesis, and hematopoiesis.
Produced by activated T cells, monocytes, and Kaposi’s sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It:
- Stimulates proliferation of fibroblasts, smooth muscle cells, and Kaposi’s sarcoma cells
- Inhibits growth of certain normal and tumor cell lines
- Promotes cytokine release (IL-6, GM-CSF, G-CSF) from endothelial cells
- Enhances expression of LDL receptors in hepatoma cells
OSM shares structural and functional similarities with LIF, IL-6, and CNTF.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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