Thermo Fisher Scientific PFKFB3 Polyclonal Antibody
PFKFB3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 면역세포염색에 적합. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상. 인간 및 생쥐 시료 반응성. 연구용으로만 사용 가능.
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Thermo Fisher Scientific PFKFB3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PFKFB3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720797 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The protein encoded by this gene belongs to a family of bifunctional enzymes involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a key regulator of glycolysis in eukaryotic cells.
PFKFB3 exhibits both 6-phosphofructo-2-kinase and fructose-2,6-bisphosphatase activities, controlling F2,6BP levels.
This protein is essential for cell cycle progression and apoptosis prevention, acting as a regulator of cyclin-dependent kinase 1 and linking glucose metabolism to cell proliferation and survival in tumor cells.
Several alternatively spliced transcript variants encoding different isoforms have been identified.
Usage Restrictions
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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