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Thermo Fisher Scientific Phospho-Retinoblastoma (Ser249, Thr252) Polyclonal Antibody
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인간 Rb 단백질의 Ser249 및 Thr252 인산화 부위를 인식하는 폴리클로날 항체입니다. Western blot에 적합하며, Protein G로 정제된 액상 형태입니다. 암 관련 Rb 단백질 연구에 활용되며, -20°C에서 보관합니다.
- 카탈로그번호
- 3112-25UG
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 05. 오전 07:32
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Thermo Fisher Scientific 3112-25UG Phospho-Retinoblastoma (Ser249, Thr252) Polyclonal Antibody 25 ug pk판매 단위 pk ·
재고 확인 필요
811,400원VAT 포함 892,540원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-Retinoblastoma (Ser249, Thr252) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 0.25–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphopeptide region of human Rb protein containing Serine 249 and Threonine 252 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% Sodium Azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine residues but not on tyrosine. It forms complexes with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may regulate transcription, and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene are implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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