Thermo Fisher Scientific MAGE1 Polyclonal Antibody
MAGE1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 암 조직에서 발현되는 MAGE1 검출에 적합하며, IHC, ELISA, IP에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:200 |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1:200–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Melanoma-associated antigen 1 protein (1–309AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.89 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_3091541 |
Target Information
Human malignant neoplasms carry rejection antigens recognized by patients' autologous, tumor-directed, cytolytic CD8+ T lymphocyte clones (CTLs).
An important group of these antigens is encoded by the MAGE family of genes. MAGE-1 is expressed in a significant proportion of human neoplasms of various histological types — including melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, and renal cell carcinomas — but not in normal tissues.
Therefore, the encoded antigen may serve as a marker for early detection and as a target for cancer immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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