Thermo Fisher Scientific Phospho-Cardiac Troponin I (Ser23, Ser24) Recombinant Rabbit Monoclonal Antibody (9G7R2)
Cardiac Troponin I의 Ser23/Ser24 인산화 부위를 특이적으로 인식하는 recombinant rabbit monoclonal antibody. IHC(P) 및 ELISA에 적합하며, Protein A로 정제된 고순도 항체. 인간 시료에 반응하며, -20°C에서 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9G7R2 |
| Immunogen | A synthetic phosphorylated peptide around S23 & S24 of human Cardiac Troponin I (TNNI3) |
| Immunogen Sequence | RRSSNY |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.59 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
This antibody specifically recognizes the phosphorylated Ser23 and Ser24 residues of human Cardiac Troponin I.
Target Information
Cardiac Troponin I (TnI) is an inhibitory protein within the cardiac muscle troponin complex, associated with troponin C (TnC) and troponin T (TnT).
It regulates muscle contraction by controlling the interaction between actin and myosin in response to calcium binding.
Measurement of TnI and TnT levels in blood is a key diagnostic indicator for myocardial injury, aiding differentiation between angina and myocardial infarction.
Mutations in the Cardiac Troponin I gene are linked to familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Additionally, Cardiac Troponin I has been shown to inhibit angiogenesis both in vivo and in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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