Thermo Fisher Scientific UBE4B Recombinant Rabbit Monoclonal Antibody (1D7K5)
UBE4B 단백질 인식용 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, 인간, 생쥐, 랫드 시료에 반응합니다. 고순도 친화 크로마토그래피 정제, -20°C 보관 안정성 우수.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA (ELISA) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1D7K5 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human UBE4B (O95155). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911733 |
Product Specific Information
Positive test controls include: PC-12, SKOV3, NIH/3T3, K-562, Mouse liver, Mouse brain, Rat liver, Rat brain.
Immunogen sequence:
MEELSADEIR RRRLARLAGG QTSQPTTPLT SPQRENPPGP PIAASAPGPS QSLGLNVHNM TPATSPIGAS GVAHRSQSSE GVSSLSSSPS NSLETQSQSL
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation.
Ubiquitination involves at least three classes of enzymes:
- Ubiquitin-activating enzymes (E1s)
- Ubiquitin-conjugating enzymes (E2s)
- Ubiquitin-protein ligases (E3s)
UBE4B represents an additional conjugation factor, E4, involved in multiubiquitin chain assembly.
UBE4B is also considered a strong candidate among neuroblastoma tumor suppressors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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