Thermo Fisher Scientific IL6 Monoclonal Antibody (OTI3G9), TrueMAB
인간 IL-6 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot, IHC, ICC/IF에 적합. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 염증 및 면역 반응 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 29–212 of human IL-6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IL-6 is a cytokine involved in inflammation and B cell maturation. It acts as an endogenous pyrogen, inducing fever in autoimmune diseases or infections. IL-6 is expressed at sites of acute and chronic inflammation, secreted into serum, and activates transcriptional inflammatory responses via the interleukin 6 receptor alpha. Dysregulation of IL-6 is implicated in various inflammation-associated diseases such as diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi Sarcoma, and Rheumatoid Arthritis. Elevated IL-6 levels have also been observed in viral infections, including COVID-19 (caused by SARS-CoV-2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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