
Thermo Fisher Scientific KV3.2 (KCNC2) Polyclonal Antibody
Thermo Fisher Scientific의 KV3.2 (KCNC2) 폴리클로날 항체로, 인간·마우스·랫트 시료에서 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다. 신경세포의 전압의존성 K+ 채널 연구에 유용합니다.
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Applications
- Western Blot (WB): Tested dilution 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DLGGKRLGIEDAAGLGGPDGK(C), corresponding to amino acid residues 184–204 of rat KV3.2, intracellular N-terminal domain |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA, 5% sucrose |
| Contains | 0.025% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 50 µL or 0.2 mL of double distilled water (DDW), depending on sample size.
- Ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For long-term storage, aliquot and store at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Voltage-gated K⁺ channels in the plasma membrane control repolarization and action potential frequency in neurons, muscles, and other excitable cells.
The KV gene family encodes over 30 proteins forming K⁺ channel subunits, varying in gating, permeation, and expression patterns.
Functional KV channels assemble as tetramers of pore-forming α-subunits (KV1, KV2, KV3, KV4, KV9) and accessory subunits that modulate channel properties.
KV3.2 is a multipass membrane protein regulating voltage-dependent K⁺ permeability of excitable membranes. Its tail may influence subcellular targeting and channel activity regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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