Thermo Fisher Scientific HNRNPM Monoclonal Antibody (OTI1F6), TrueMAB
Human HNRNPM 단백질을 인식하는 단클론 항체로 Western blot 및 IHC(P) 실험에 적합합니다. Unconjugated 형태, 고순도 친화 크로마토그래피 정제, 안정적인 PBS/BSA/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F6 |
| Immunogen | Human recombinant protein fragment (aa 1–261 of HNRNPM, produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Heterogeneous nuclear ribonucleoproteins (hnRNPs) directly bind to nascent RNA polymerase II transcripts and play a key role in transcript-specific packaging and alternative splicing of pre-mRNAs. The M1–M4 proteins form a cluster of four abundant hnRNPs that bind avidly to poly(G) and poly(U) RNA homopolymers. These M proteins belong to the ribonucleoprotein consensus sequence family, showing similarity to RNA-binding proteins from Saccharomyces cerevisiae. They possess a methionine/arginine-rich hexapeptide repeat motif (MR repeat) similar to the 64 kDa subunit of cleavage stimulation factor involved in 3′-end maturation of pre-mRNAs. Proteins immunologically related to M exist across eukaryotes from human to yeast.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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