Thermo Fisher Scientific ACTR1B Polyclonal Antibody
ACTR1B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 친화 크로마토그래피 정제. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–105 of human ACTR1B (NP_005726.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.86 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901270 |
Product Specific Information
- Positive Samples: Mouse thymus, Mouse brain, Mouse heart, Rat lung
- Immunogen sequence:
MESYDIIANQ PVVIDNGSGV IKAGFAGDQI PKYCFPNYVG RPKHMRVMAG ALEGDLFIGP KAEEHRGLLT IRYPMEHGVV RDWNDMERIW QYVYSKDQLQ TFSEE
Target Information
This gene encodes a 42.3 kDa subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in various cellular functions, including:
- ER-to-Golgi transport
- Centripetal movement of lysosomes and endosomes
- Spindle formation and chromosome movement
- Nuclear positioning and axonogenesis
This subunit, like ACTR1A, is an actin-related protein. These two proteins share 90% amino acid identity and are present in a constant ratio of approximately 1:15 in the dynactin complex.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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