Thermo Fisher Scientific IL17RA Polyclonal Antibody, FITC
IL17RA 단백질을 인식하는 FITC 결합 다클론 항체로, 인간·생쥐·랫트 시료에 반응. WB, ELISA, IP 등 다양한 면역분석에 사용 가능. 형광 특성(498/517 nm)으로 세포 분석 및 단백질 검출에 적합. -20°C 암저장 조건에서 안정적.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 90–140 on IL17RA protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It induces maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a type I membrane glycoprotein that binds IL-17A and IL-17F with low affinity. IL-17A and its receptor are implicated in inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA cause familial candidiasis type 5 (CANDF5), characterized by altered immune responses and impaired fungal clearance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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