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Thermo Fisher Scientific CD49f Monoclonal Antibody (NKI-GoH3)
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Thermo Fisher Scientific CD49f Monoclonal Antibody (NKI-GoH3)

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CD49f (Integrin alpha 6) 단백질을 인식하는 NKI-GoH3 클론의 Rat IgG2a 단클론 항체. IHC, ICC/IF, Flow Cytometry, IP 등 다양한 응용에 적합. Protein G 정제, 1 mg/mL 농도의 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 가능.

카탈로그번호
MA516884
판매단위
pk
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마지막 업데이트 2025. 08. 05. 오후 02:21
Thermo Fisher Scientific MA516884 CD49f Monoclonal Antibody (NKI-GoH3) 100 ug pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific CD49f Monoclonal Antibody (NKI-GoH3)

Applications and Tested Dilution

Application Tested Dilution Publications
Immunohistochemistry (IHC) - 1 publication
Immunohistochemistry (Frozen) (IHC (F)) Assay-dependent -
Immunocytochemistry (ICC/IF) Assay-dependent 2 publications
Flow Cytometry (Flow) 1:50–1:200 -
Immunoprecipitation (IP) Assay-dependent -

Product Specifications

항목 내용
Species Reactivity Dog, Cynomolgus monkey, Human, Mouse, Sheep, Pig
Published Species Goat, Human, Mouse
Host / Isotype Rat / IgG2a
Class Monoclonal
Type Antibody
Clone NKI-GoH3
Immunogen BALB/c mouse mammary tumour cells expressing CD49f (Integrin alpha 6)
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Protein G
Storage Buffer PBS
Contains <0.1% sodium azide
Storage Conditions Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles.
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2538362

Additional Formats


Product Specific Information

  • For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
  • A suggested positive control for immunohistochemical applications is human tonsil.

Target Information

CD49f (Integrin alpha-6, ITGA6) is an integrin alpha chain protein that forms part of integrin receptors involved in cell adhesion and signaling.

  • Integrins are composed of alpha and beta subunits, forming structural and functional linkages between the extracellular matrix (ECM) and intracellular cytoskeletal proteins.
  • Alpha 6 can pair with beta 4 (forming TSP180) or beta 1 (forming VLA-6).
  • These complexes mediate intracellular signaling affecting cell shape, mobility, and cell cycle progression.
  • CD49f is predominantly expressed in epithelial cells and plays a structural role in hemidesmosomes.
  • Over 18 alpha and 8 beta subunits with multiple splice variants have been identified in mammals.
  • Integrins also mediate cell-cell adhesion through interactions with ICAMs, promoting cell aggregation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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