Thermo Fisher Scientific TLX3 Polyclonal Antibody
TLX3 단백질을 검출하기 위한 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot 및 IHC(P)에서 사용 가능하며, 인간 및 마우스에 반응합니다. 고순도 항원 친화 크로마토그래피 정제 제품으로 장기 보관 시 -20°C에서 안정적입니다.
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Thermo Fisher Scientific TLX3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human TLX3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792714 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Xenopus laevis (100%), Chicken (100%), Bovine (100%).
- Positive Control: SK-N-SH, IMR32, SK-N-AS.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes.
TLX3, also known as homeobox11-like1 (HOX11L2), is a DNA-binding nuclear transcription factor expressed in a subset of the primary sensory nervous system.
TLX3, along with TLX1, promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype opposing LBX1 signals during dorsal spinal cord development.
Chromosomal translocations of the TLX3 gene have been shown to result in some forms of T-cell acute lymphoblastic leukemia (T-ALL).
Safety and Regulatory Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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