Thermo Fisher Scientific ARID1A Polyclonal Antibody
ARID1A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, IP, ChIP 등 다양한 응용에 적합. 인간 반응성, 높은 순도, 항원 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ARID1A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
| ChIP assay (ChIP) | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human ARID1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.53 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792708 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (81%), Bovine (84%).
- Positive Control: 293T, A431, HeLa, A549, HepG2, HepG2 nuclear extract.
- Centrifuge briefly prior to opening the vial.
- Store product as a concentrated solution.
Target Information
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.
The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, required for transcriptional activation of genes normally repressed by chromatin.
It possesses at least two conserved domains important for its function:
- A DNA-binding domain that specifically binds AT-rich DNA sequences recognized by the SNF/SWI complex at the beta-globin locus.
- A C-terminus region that stimulates glucocorticoid receptor-dependent transcriptional activation.
The protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through protein-DNA or protein-protein interactions.
Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음 또는 제거됨)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.