Thermo Fisher Scientific MTHFD2 Polyclonal Antibody
MTHFD2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography로 정제. 연구용으로만 사용.
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Thermo Fisher Scientific MTHFD2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human MTHFD2 (Accession P13995), amino acid residues G42–A92 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2854008 |
Product Specific Information
Antibody detects endogenous levels of total MTHFD2.
Target Information
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities.
The enzyme functions as a homodimer and requires magnesium and inorganic phosphate for activity. Formation of the enzyme–magnesium complex allows NAD binding.
Alternative splicing produces two transcripts, one protein-coding and one non-coding. A pseudogene is located on chromosome 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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