Thermo Fisher Scientific BCL6 Monoclonal Antibody (PCRP-BCL6-1B1)
인간 BCL6 단백질을 인식하는 Mouse IgG2b 단클론 항체로, Flow Cytometry와 Peptide Array에 사용 가능. HeLa 및 MCF-7 세포에서 양성 대조로 활용되며, 핵 및 미토콘드리아 위치 검출에 적합. 연구용으로만 사용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-BCL6-1B1 |
| Immunogen | Recombinant fragment (around aa528–601) of human BCL6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: HeLa or MCF-7 cells
- Cellular Location: Nucleus, Mitochondria
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and rearrangements have been detected in 33%–45% of diffuse large B cell lymphomas.
It has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas, and in nodular lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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