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Thermo Fisher Scientific Bcl-6 Monoclonal Antibody (BCL6, 1982)
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인간 Bcl-6 단백질을 인식하는 Mouse 모노클로날 항체로, IHC 및 ELISA에 사용 가능. 고순도 Protein A/G 정제, PBS 버퍼에 보존제 없이 제공. 비결합형 액상 형태로 연구용에 적합.
- 카탈로그번호
- 604-MSM12-P1ABX
- 판매단위
- pk
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Thermo Fisher Scientific 604-MSM12-P1ABX Bcl-6 Monoclonal Antibody (BCL6, 1982) 100 ug pk판매 단위 pk ·
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825,100원VAT 포함 907,610원
Thermo Fisher Scientific · Thermo Fisher Scientific Bcl-6 Monoclonal Antibody (BCL6, 1982)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BCL6, 1982 |
| Immunogen | Recombinant human Bcl-6 protein fragment (around aa256–389) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Tested in direct ELISA (use antibody at 2–4 µg/mL for coating).
- For immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
Bcl-6 proto-oncogene product is a Kruppel-type zinc-finger protein expressed mainly in normal germinal center B cells and related lymphomas.
It is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, with Bcl-6 rearrangements detected in 33–45% of diffuse large B cell lymphomas.
Immunohistochemical detection of Bcl-6 has been reported in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas, and nodular lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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