Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1 Polyclonal Antibody
SARS-CoV-2 스파이크 단백질 S1을 인식하는 토끼 폴리클로날 항체. Western blot, ICC/IF, ELISA, 기능 분석에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS에 0.02% sodium azide 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–4 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
| ELISA | 1–10 µg/mL |
| Functional Assay | 0.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Anti-SARS-CoV-2 (COVID-19) Spike Antibody (cleavage site) was raised against a peptide corresponding to 12 amino acids near the center of SARS-CoV-2 (COVID-19) Spike glycoprotein. The immunogen is located within 650–700 amino acids of SARS-CoV-2 (COVID-19) Spike protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890576 |
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV (2019 Novel Coronavirus), is a virus that causes illnesses ranging from mild cold symptoms to severe respiratory distress and death. The SARS-CoV-2 Spike Protein consists of S1 and S2 domains and serves as the main surface antigen of the coronavirus. The glycosylated Spike protein, along with the nucleocapsid protein, can be detected in infected cell culture supernatants using antisera from SARS patients. The S1 domain contains a receptor-binding domain (RBD) that specifically binds to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. The diversity of coronaviruses is reflected in the variability of their Spike proteins, which have evolved to differ in receptor interactions and responses to environmental triggers of virus-cell membrane fusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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