Thermo Fisher Scientific Brevican Polyclonal Antibody
Rabbit polyclonal antibody targeting human Brevican protein. Validated for WB and IHC(P) applications. High specificity and affinity-purified. Supplied in liquid form with PBS and glycerol buffer. For research use only.
- 카탈로그번호
- PA531444
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 83–302 of Human Brevican |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548918 |
Product Specific Information
- Recommended positive controls: BCAN-transfected 293T
- Predicted reactivity: Mouse (92%), Rat (93%), Dog (97%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It belongs to the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. Highly expressed in the central nervous system, Brevican is thought to stabilize synapses and inhibit neural plasticity. It is secreted from astrocytes and neurons as a 145 kD core protein, with or without CS chains. Cleavage by extracellular glutamyl endopeptidases (ADAMTSs) produces a 55 kD N-terminal fragment containing the unique C-terminal epitope EAMESE.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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