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Thermo Fisher Scientific Phospho-LKB1 (Ser428) Polyclonal Antibody
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Phospho-LKB1 (Ser428) 폴리클로날 항체로 인간, 마우스, 랫트 반응성. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Protein A 정제, 1 mg/mL 농도, 액상 형태로 제공. 암 연구 및 세포 신호전달 연구에 유용.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 07:17
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Thermo Fisher Scientific BS-3249R Phospho-LKB1 (Ser428) Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
569,000원VAT 포함 625,900원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-LKB1 (Ser428) Polyclonal Antibody
Thermo Fisher Scientific Phospho-LKB1 (Ser428) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human LKB1 around the phosphorylation site of Ser428 [RL(p-S)AC] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LKB1 (also known as STK11, Serine/threonine-protein kinase STK11) is a tumor suppressor and a member of the serine/threonine kinase family.
It physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
LKB1 is located in both cytoplasm and nucleus, translocating to mitochondria during apoptosis.
It acts as a master upstream kinase regulating AMPK and AMPK-related kinases.
Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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