Thermo Fisher Scientific CD79a (B Cell Marker) Monoclonal Antibody (JCB117, HM47/A9)
CD79a 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체로, B 세포 마커 연구에 적합. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용 가능. 인간, 마우스, 랫, 원숭이 등 다종 반응성. 단백질 A/G 정제, PBS 용액 형태, 보존제 무첨가.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Pig, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | JCB117, HM47/A9 |
| Immunogen | Synthetic peptide corresponding to amino acids 202–216 (GTYQDVGSLNIADVQ) of human CD79a protein (JCB117 and HM47/A9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD79a is a disulphide-linked heterodimer that includes the B29 (CD79b) polypeptide. It functions as part of the B lymphocyte antigen receptor complex, associating with Ig-alpha and Ig-beta, which are essential for receptor expression and signaling. CD79a expression begins at the pre-B cell stage and continues through to the plasma cell stage, where it remains intracellular. It is typically found in precursor B-cell acute leukemias, B cell lines, B cell lymphomas, and some myelomas, but absent in myeloid or T cell lines.
Diseases associated with CD79a include:
- Agammaglobulinemia 3
- Agammaglobulinemia, Non-Bruton type
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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