Thermo Fisher Scientific GORAB Polyclonal Antibody
Human GORAB 단백질을 표적으로 하는 Rabbit IgG 폴리클로날 항체로, IP 등 다양한 연구용 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C에서 보관하며 연구용으로만 사용됩니다.
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Applications
Immunoprecipitation (IP)
- Tested Dilution: 8–15 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 60 and 110 of human RAB6-interacting golgin (GORAB) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
TCEB1, known as protein elongin C, is a subunit of the transcription factor B (SIII) complex composed of elongins A/A2, B, and C.
This complex activates elongation by RNA polymerase II by suppressing transient pausing within transcription units.
Elongin A acts as the transcriptionally active component, while elongins B and C serve as regulatory subunits.
Elongin A2 is expressed specifically in the testis and forms a stable complex with elongins B and C.
The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, inhibiting transcription elongation.
Western blot tests using antibodies against distinct regions of this protein confirm consistent molecular weight.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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