Thermo Fisher Scientific TRPM2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TRPM2 (residues 650–700). Validated for WB and IP applications. Unconjugated, liquid form at 1 mg/mL concentration. Stable for 1 year at 4°C; shipped on wet ice.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 650 and 700 of Human Transient Receptor Potential Cation Channel, Subfamily M, Member 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
TRPM2 belongs to the ion transport protein family, which includes sodium, potassium, and calcium ion channels. This family is characterized by proteins possessing six transmembrane helices, where the last two helices flank a loop determining ion selectivity.
TRPM2 is activated by oxidative stress and confers susceptibility to cell death. It functions as a calcium-permeable cation channel regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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