Thermo Fisher Scientific alpha Adducin Polyclonal Antibody
Human ADD1(adducin 1)에 특이적인 Rabbit Polyclonal Antibody. IHC(P)에서 1:200~1:1,000 희석 비율로 사용 가능. 단백질 A 및 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 4°C 또는 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of the Human ADD1/adducin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2787646 |
Product Specific Information
This antibody has specificity for Human ADD1/adducin 1.
Target Information
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein composed of related subunits produced from distinct genes but sharing a similar structure.
Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region.
Alpha- and gamma-adducins are ubiquitously expressed, whereas beta-adducin is expressed at high levels in brain and hematopoietic tissues.
Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.
Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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