Thermo Fisher Scientific HMBS Polyclonal Antibody
HMBS 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot과 IHC(Paraffin) 실험에 적합합니다. 사람, 마우스, 랫트에 반응하며 Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific HMBS Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human HMBS/PBGD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PBGD (porphobilinogen deaminase), also known as hydroxymethylbilane synthase, is a cytoplasmic enzyme involved in the heme synthesis pathway. PBGD belongs to the HMBS family. Deficiency of PBGD leads to errors in pyrrole metabolism, causing acute intermittent porphyria (AIP), an inherited autosomal disorder characterized by acute neurological dysfunctions, hypertension, tachycardia, peripheral neuropathy, abdominal pain, and elevated aminolevulinic acid and porphobilinogen levels in urine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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