Thermo Fisher Scientific FBLIM1 Polyclonal Antibody
FBLIM1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도의 Affinity chromatography 정제 방식으로 제조되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FBLIM1 (Accession Q8WUP2), corresponding to amino acid residues F299–Q349. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850029 |
Product Specific Information
Antibody detects endogenous levels of total FBLIM1.
Target Information
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and multiple C-terminal LIM domains. The protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. It may be involved in the assembly and stabilization of actin filaments and plays a role in modulating cell adhesion, morphology, and motility. Additionally, it localizes to the nucleus and may influence cardiomyocyte differentiation by binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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