Thermo Fisher Scientific IL-13 Polyclonal Antibody
IL-13 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 검증됨. 인간 및 마우스 반응성. 고순도 친화 크로마토그래피로 정제된 액상 항체. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5100831
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IL13 (Accession P35225), corresponding to amino acid residues L9–A59 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850332 |
Product Specific Information
Antibody detects endogenous levels of total IL13.
Target Information
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, involved in regulating inflammatory and immune responses. It down-regulates macrophage activity, inhibiting production of pro-inflammatory cytokines and chemokines, and plays a role in allergen-induced asthma independent of IgE and eosinophils. IL-13 also regulates B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching. Structurally, IL-13 resembles IL-3, IL-4, IL-5, and GM-CSF. The IL13 gene is part of a cytokine gene cluster on chromosome 5q, located near IL4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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