Thermo Fisher Scientific EPB41L2/4.1G Polyclonal Antibody
EPB41L2/4.1G 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체. Western blot과 Immunoprecipitation에 적합하며, 비결합형 액상 형태로 제공. 세포골격 단백질 연구 및 신경계 단백질 분석에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 575 and 625 of human erythrocyte membrane protein band 4.1-like 2 (Generally expressed protein 4.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N, and 4.1B), predominantly expressed in the nervous system.
4.1G stabilizes spectrin–actin interactions and is associated with hereditary elliptocytosis.
4.1R is essential for maintaining erythrocyte shape and membrane mechanical properties.
Both 4.1R and 4.1G are distributed in the cerebellum and modulate neuronal membrane properties by promoting fodrin/actin association.
4.1N (EPB41L1) and 4.1B (EPB41L3) are strongly expressed in the brain. Antibodies to 4.1N detect multiple forms enriched in postsynaptic density, while antibodies to 4.1B detect two forms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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