Thermo Fisher Scientific OX40L Monoclonal Antibody (OX89), FITC
Mouse 시료에서 CD134L/OX40L을 검출하는 FITC 결합 단클론 항체. Flow Cytometry용으로 최적화되어 있으며, 단백질 G 정제 및 안정적인 PBS/BSA 버퍼에 보관. 498/517 nm 형광 특성으로 높은 감도와 명확한 신호 제공.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1.0 µg/1x10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX89 |
| Immunogen | CD4.CD134L chimeric protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at −20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539296 |
Additional Formats
- Unconjugated ([MA5-17910])
- Biotin ([MA5-17911])
- PE ([MA5-17913])
- Request custom conjugation (Thermo Fisher form)
Product Specific Information
MA5-17912 targets CD134L/OX40L in FACS applications and shows reactivity with Mouse samples.
The immunogen used is a CD4.CD134L chimeric protein.
Target Information
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane-bound, non-covalently linked homotrimeric protein.
It is expressed on antigen-presenting cells such as dendritic cells and activated B-cells, and also on vascular endothelial cells, mast cells, and natural killer cells.
TNFSF4 signals specifically through the TNFRSF4 receptor, expressed predominantly on CD4+ T cells and certain activated CD8+ T cells.
TNFRSF4/TNFSF4 functions as a costimulatory signal required for productive interaction between antigen-presenting cells and target T-cells, enhancing proliferation, survival, and expression of RANTES, IL-2, IL-3, and IFNγ.
This signaling pathway plays a crucial role in immunotolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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