Thermo Fisher Scientific OX40L Monoclonal Antibody (OX89), Biotin
Mouse OX40L 단백질을 표적으로 하는 Biotin 결합 단클론 항체. Flow Cytometry 및 Immunohistochemistry에 적합. 단백질 G로 정제된 고순도 항체로 안정적인 신호 검출 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific OX40L Monoclonal Antibody (OX89), Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | Assay-dependent |
| Flow Cytometry (Flow) | 1.0 µg/1×10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX89 |
| Immunogen | CD4.CD134L chimeric protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539295 |
Additional Formats
Product Specific Information
MA5-17911 targets CD134L/OX40L in FACS and IHC applications and shows reactivity with Mouse samples.
The MA5-17911 immunogen is CD4.CD134L chimeric protein.
Target Information
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane-bound, non-covalently linked homotrimeric protein. It is expressed on antigen-presenting cells such as dendritic cells and activated B-cells, as well as on vascular endothelial cells, mast cells, and natural killer cells.
TNFSF4 signals specifically through the TNFRSF4 receptor, expressed predominantly on CD4⁺ T cells and certain activated CD8⁺ T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal required for productive interaction between antigen-presenting cells and target T cells, enhancing proliferation and survival, and increasing expression of RANTES, IL-2, IL-3, and IFN-γ.
TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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