Thermo Fisher Scientific CASC3 Polyclonal Antibody
Thermo Fisher Scientific의 CASC3 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. KLH 결합 합성 펩타이드 유래 면역원으로 제작된 Rabbit IgG 폴리클로날 항체입니다. 고순도 Protein A 정제, 안정적인 액상 형태로 연구용에 최적화되어 있습니다.
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Thermo Fisher Scientific CASC3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CASC3/MLN51, amino acids 501–600 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator. The 20S core consists of four rings of 28 non-identical subunits—two rings of seven alpha subunits and two rings of seven beta subunits. The 19S regulator includes a base (six ATPase subunits and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits). Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome, a modified proteasome, processes class I MHC peptides and contains the 11S regulator (PA28) instead of the 19S regulator. This gene encodes the gamma subunit of the 11S regulator, forming a homohexameric ring. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: BS-4097R_CASC3_O15234-1_Rabbit.svg, BS-4097R_CASC3_O15234-1_Rabbit_PDP.jpeg)
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