Thermo Fisher Scientific CASC3 Polyclonal Antibody
Thermo Fisher Scientific의 CASC3 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. KLH 결합 합성 펩타이드 유래 면역원으로 제작된 Rabbit IgG 폴리클로날 항체입니다. 고순도 Protein A 정제, 안정적인 액상 형태로 연구용에 최적화되어 있습니다.
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Thermo Fisher Scientific CASC3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CASC3/MLN51, amino acids 501–600 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator. The 20S core consists of four rings of 28 non-identical subunits—two rings of seven alpha subunits and two rings of seven beta subunits. The 19S regulator includes a base (six ATPase subunits and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits). Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome, a modified proteasome, processes class I MHC peptides and contains the 11S regulator (PA28) instead of the 19S regulator. This gene encodes the gamma subunit of the 11S regulator, forming a homohexameric ring. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: BS-4097R_CASC3_O15234-1_Rabbit.svg, BS-4097R_CASC3_O15234-1_Rabbit_PDP.jpeg)
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