Thermo Fisher Scientific WSB1 Polyclonal Antibody
Rat WSB1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. 합성 펩타이드 면역원으로 제작되었으며, 0.5 mg/mL 농도의 액상 형태. PBS(2% sucrose) 버퍼에 보관하며, -20°C에서 저장 필요. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of rat WSB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691314 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 100%
Target Information
WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein containing one SOCS box domain and six WD repeats. Expressed as multiple alternatively spliced isoforms, WSB1 functions as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins such as DIO2.
Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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