Thermo Fisher Scientific Opsin 3 Polyclonal Antibody
인간 Opsin 3 단백질을 인식하는 토끼 다클론 항체로, IHC(P)에서 5–8 µg/mL 농도로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 내 0.1% sodium azide 포함. 뇌 및 다양한 조직에서의 Opsin 3 발현 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–8 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminus of human OPN3 / Encephalopsin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551397 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gibbon, Monkey, Marmoset (94%), Panda (81%)
Target Information
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily.
In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues.
The Opsin 3 gene is strongly expressed in brain and testis, and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. It may also be expressed in the retina. The protein exhibits canonical features of a photoreceptive opsin and may play a role in encephalic photoreception.
Strong expression is observed in the preoptic area and paraventricular nucleus of the hypothalamus, as well as in selective brain regions such as the cerebral cortex, cerebellar Purkinje cells, subsets of striatal neurons, thalamic nuclei, and spinal cord interneurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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