Thermo Fisher Scientific F1A alpha Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:5,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human F1A alpha. Recombinant protein control fragment (Product #RP-98129). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:F1A alpha,uniProtId:Q9UK73-1,ncbiNodeId:9606,antigenRange:387-476,antigenLength:627,antigenImageFileName:PA5-59906_F1A_alpha_Q9UK73-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59906_F1A_alpha_Q9UK73-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641187

Product Specific Information

Immunogen sequence: RFAQVFSQMI HLNETVKAPD IECVLRCSVL EIEQSMNRVK NISDADVHNA MDNYECNLYT FLYLVCISTK TQCSEEDQCK INKQIYNLIH

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1-b. F1Aalpha/FEM1-b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase. FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.