Thermo Fisher Scientific Phospho-ALOX5 (Ser271) Polyclonal Antibody
Phospho-ALOX5 (Ser271) 항체로 인간 시료에 반응하며, Western blot 및 ELISA에 적합. Rabbit polyclonal IgG로 제작되었으며, 친화 크로마토그래피로 정제됨. PBS/glycerol 버퍼에 보관되며 -20°C에서 안정적. 염증 반응 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S271 of human ALOX5 (NP_0006891) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.43 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901832 |
Product Specific Information
- Positive Samples: HT-29 + EGF, HT-29 + PMA
- Immunogen sequence: QLSLE
Target Information
This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis, and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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