Thermo Fisher Scientific Human BCAR3 Synthetic Peptide
Human BCAR3 단백질의 아미노 말단 16개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. PA5-34425 항체의 차단 펩타이드로 사용 가능하며, 인간 유래 시료에 반응합니다. 연구용으로만 사용되며, 액상 형태로 -20°C에서 보관합니다.
- 카탈로그번호
- PEP1467
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 16 amino acid sequence near the amino terminus of human BCAR3.
PEP-1467 can be used as a blocking peptide with polyclonal antibody PA5-34425.
Target Information
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers may progress to become anti-estrogen resistant.
Breast cancer anti-estrogen resistance gene 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance.
The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells.
The protein contains a putative src homology 2 (SH2) domain, a hallmark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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