Thermo Fisher Scientific SMC1A Monoclonal Antibody (OTI11E1), TrueMAB
SMC1A 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB 및 IHC(P) 실험에 적합함. 인간 및 생쥐 시료 반응성. 고순도 친화 크로마토그래피 정제. 안정적인 액상 형태로 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 889–1016 of human SMC1A produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression. These proteins are conserved in eukaryotes and are essential for mitotic chromosome dynamics.
SMC1 and SMC3 form a heterodimeric complex required for metaphase progression and sister chromatid cohesion during mitosis. Mutations in the SMC1A gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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