Thermo Fisher Scientific ZIP Kinase Polyclonal Antibody, Biotin
ZIP Kinase(DAPK3) 단백질을 표적으로 하는 Thermo Fisher Scientific의 Biotin 결합 폴리클로날 항체입니다. Western blot, ELISA, IP 등 다양한 응용에 적합하며, 고순도 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
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Thermo Fisher Scientific ZIP Kinase Polyclonal Antibody, Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 400–448 of mouse Death-associated protein kinase 3 (DAPK3) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
DAPK3 (Death-associated protein kinase 3) is a serine/threonine kinase involved in cell motility, smooth muscle contractility, and cell death. Encoded by ZIPK, DAPK3 is a component of desmosomes and the epidermal cornified envelope in keratinocytes. Its N-terminal domain interacts with the plasma membrane, and the C-terminal domain associates with intermediate filaments. Through its rod domain, DAPK3 forms complexes with envoplakin, linking the cornified envelope, desmosomes, and intermediate filaments. It also interacts with AKT1/PKB, suggesting a role in AKT1-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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