Thermo Fisher Scientific Uteroglobin Recombinant Rabbit Monoclonal Antibody (JU34-03)
Recombinant rabbit monoclonal antibody (clone JU34-03) specific for human Uteroglobin (SCGB1A1). Validated for WB, IHC-P, ICC/IF, and Flow Cytometry. Produced in HEK293 cells, purified by Protein A, supplied as 1 mg/mL liquid. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JU34-03 |
| Immunogen | Synthetic peptide within Human SCGB1A1 (aa 42–91) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2848533 |
Product Specific Information
Positive Control: A549, A431, HUVEC, mouse lung tissue lysate.
Target Information
Uteroglobin (also known as Clara cell phospholipid-binding protein) is a member of the Secretoglobin superfamily. It is a multifunctional protein with anti-inflammatory and anti-tumorigenic properties, binding small hydrophobic molecules such as phospholipids and prostaglandins. This small, non-glycosylated protein is highly expressed in pre-implantation embryos and secreted by non-ciliated Clara cells in pulmonary airways and other epithelial tissues. Members of the Secretoglobin family are small, secretory homo- or heterodimers with high structural conservation. Uteroglobin participates in sequestering pro-inflammatory mediators and carcinogens and has been implicated in inhibiting cell migration, invasion, platelet aggregation, and T cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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