Thermo Fisher Scientific NCAPD2 Recombinant Rabbit Monoclonal Antibody (JE62-22)
NCAPD2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간 시료 반응성이 있으며, HEK293 세포에서 발현되었습니다. Protein A로 정제된 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE62-22 |
| Immunogen | Recombinant protein within human NCAPD2 aa 51–200/1,401 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931277 |
Target Information
Regulatory subunit of the condensin complex, required for conversion of interphase chromatin into mitotic-like condensed chromosomes. The condensin complex introduces positive supercoils into relaxed DNA and converts nicked DNA into positive knotted forms. It may target the condensin complex to DNA via its C-terminal domain and promote resolution of double-strand DNA catenanes between sister chromatids. Condensin-mediated compaction increases tension in catenated sister chromatids, aiding topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. In neurogenesis, plays an essential role in accurate mitotic chromosome condensation in neuron stem cells, affecting neuron pool and cortex size. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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